SCHEMBL2224853

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2221738	0.92	S1PR1 (0.56)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL2224910	0.91	KDM4E (0.56)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL14485706	0.89	MAPT (0.59)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL2223644	0.87	KDM4E (0.61)	MAPTL3MBTL1NPSR1KDM4EPOLB
	SCHEMBL2228927	0.87	KDM4E (0.56)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL14632666	0.87	MAPT (0.59)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL2222936	0.86	MEN1 (0.57)	MAPTL3MBTL1NPSR1KDM4EPOLB
	SCHEMBL2223860	0.86	KDM4E (0.50)	MAPTL3MBTL1NPSR1KDM4EPOLB
	SCHEMBL2222641	0.85	MAPT (0.51)	S1PR1S1PR5MAPTL3MBTL1NPSR1
	SCHEMBL2226190	0.85	MAPT (0.60)	MAPTL3MBTL1NPSR1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.