Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224858 | 1.00 | NR1I2 (0.67) | NR1I2CYP2E1 | |
| SCHEMBL102077 | 0.92 | NR1I2 (0.71) | NR1I2CYP2E1 | |
| SCHEMBL134450 | 0.92 | NR1I2 (0.71) | NR1I2CYP2E1 | |
| SCHEMBL15498203 | 0.91 | NR1I2 (0.69) | NR1I2CYP2E1 | |
| SCHEMBL15233239 | 0.91 | NR1I2 (0.69) | NR1I2CYP2E1 | |
| SCHEMBL12949713 | 0.91 | NR1I2 (0.69) | NR1I2CYP2E1 | |
| SCHEMBL15498324 | 0.91 | NR1I2 (0.69) | NR1I2CYP2E1 | |
| SCHEMBL15510944 | 0.91 | NR1I2 (0.57) | NR1I2CYP2E1 | |
| SCHEMBL15511470 | 0.91 | NR1I2 (0.65) | NR1I2CYP2E1 | |
| SCHEMBL15498249 | 0.91 | NR1I2 (0.65) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523951-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011088303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES , INC. (US) | 2011-07-21 | — | — | WO | disclosed |