Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 5/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236164 | 1.00 | JAK1 (0.37) | JAK1HRH3ROCK2NAMPTATM | |
| SCHEMBL30276540 | 0.93 | JAK1 (0.38) | JAK1HRH3ROCK2NAMPTPARP1 | |
| SCHEMBL30276597 | 0.90 | ATM (0.32) | JAK1HRH3NAMPTATMFAAH | |
| SCHEMBL22235950 | 0.89 | JAK1 (0.37) | JAK1HRH3ROCK2TEAD1ENPP2 | |
| SCHEMBL30401127 | 0.89 | PARP1 (0.42) | JAK1NAMPTATMPARP1PARP2 | |
| SCHEMBL22249207 | 0.89 | JAK1 (0.36) | JAK1HRH3ROCK2NAMPTATM | |
| SCHEMBL30276467 | 0.89 | JAK1 (0.36) | JAK1HRH3ROCK2NAMPTATM | |
| SCHEMBL30276616 | 0.88 | JAK1 (0.36) | JAK1HRH3ROCK2ENPP2FAAH | |
| SCHEMBL22236184 | 0.88 | POLB (0.36) | ROCK2FAAH | |
| SCHEMBL30276416 | 0.87 | JAK1 (0.38) | JAK1HRH3ROCK2NAMPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |