Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 18/20 | 0.76 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.66 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26760893 | 1.00 | NR1H4 (0.76) | NR1H4GPBAR1PRKCD | |
| SCHEMBL23284050 | 0.87 | GPBAR1 (0.73) | GPBAR1PRKCD | |
| SCHEMBL22251678 | 0.86 | NR1H4 (1.00) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22251560 | 0.86 | NR1H4 (1.00) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22251691 | 0.86 | NR1H4 (0.65) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22251708 | 0.86 | NR1H4 (0.65) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22251648 | 0.86 | NR1H4 (0.57) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22268569 | 0.85 | NR1H4 (0.59) | NR1H4GPBAR1 | |
| SCHEMBL22251744 | 0.84 | NR1H4 (0.68) | NR1H4GPBAR1PRKCD | |
| SCHEMBL22251562 | 0.83 | NR1H4 (0.86) | NR1H4GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192916-B2 | Pentacyclic triterpene compound and preparation method therefor, and pharmaceutical composition and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-12-07 | — | — | US | disclosed |
| US-20200231623-A1 | PENTACYCLIC TRITERPENE COMPOUND AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231623-A1 | PENTACYCLIC TRITERPENE COMPOUND AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | NR1H4, CYP4A11, GPBAR1 | NR1H4 1/4885GPBAR1 3/4885PRKCD 1147/4885 |
| US-11192916-B2 | Pentacyclic triterpene compound and preparation method therefor, and pharmaceutical composition and use thereof | NR1H4, CYP4A11, GPBAR1 | NR1H4 1/4885GPBAR1 3/4885PRKCD 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.