Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24724925 | 1.00 | POLB (0.44) | POLBHDAC1HDAC6HPGDMME | |
| SCHEMBL15037249 | 0.85 | ESR1 (0.51) | — | |
| SCHEMBL10258739 | 0.85 | ESR1 (0.51) | — | |
| SCHEMBL2617244 | 0.85 | F2 (0.43) | ALDH1A1 | |
| SCHEMBL10198456 | 0.84 | MAPT (0.45) | HDAC1HDAC6HPGDMMEEPHX1 | |
| SCHEMBL27917917 | 0.84 | MAPT (0.45) | HDAC1HDAC6HPGDMMEEPHX1 | |
| SCHEMBL22255858 | 0.84 | SLC6A4 (0.56) | ACACBKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL14532451 | 0.84 | ANPEP (0.41) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15092147 | 0.84 | ESR1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL15092149 | 0.84 | ESR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911645-B1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIV LILLE (FR) | 2022-12-07 | — | — | EP | disclosed |
| WO-2020148403-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIVERSITE DE LILLE (FR) | 2020-07-23 | — | — | WO | disclosed |