SCHEMBL2225637

SCHEMBL2225637

CC(C)CC(NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 1.00
FNTB P49356 18/20 1.00
PGGT1B P53609 17/20 1.00
TDP1 Q9NUW8 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16136646 1.00 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL30144590 1.00 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL4738546 1.00 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL8495867 1.00 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL14169166 0.93 FNTA (0.87) FNTAFNTBPGGT1BTDP1
SCHEMBL9058589 0.91 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL16136645 0.91 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL29642927 0.91 FNTA (1.00) FNTAFNTBPGGT1BTDP1
SCHEMBL1802360 0.91 FNTA (1.00) FNTAFNTBPGGT1BTDP1
Hydrochloric Acid SCHEMBL8496569 0.91 FNTA (0.98) FNTAFNTBPGGT1BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011088126-A2 TREATMENT OF VIRAL INFECTION WITH PRENYLTRANSFERASE INHIBITORS EIGER BIOPHARMACEUTICALS, INC. (US) 2011-07-21 WO disclosed