Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256591 | 0.90 | SLCO1B1 (0.67) | SLCO1B1ABCB11MEN1KMT2AAPP | |
| SCHEMBL24042962 | 0.89 | SLCO1B1 (0.45) | SLCO1B1ABCB11KMT2ANPC1RAB9A | |
| SCHEMBL24042784 | 0.88 | SLCO1B1 (0.43) | SLCO1B1ABCB11MAPTMEN1KMT2A | |
| SCHEMBL22256627 | 0.88 | SLCO1B1 (0.42) | SLCO1B1ABCB11LMNAMEN1KMT2A | |
| SCHEMBL22256657 | 0.86 | SLCO1B1 (0.54) | SLCO1B1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL24287896 | 0.86 | SLCO1B1 (0.54) | SLCO1B1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL22256654 | 0.86 | SLCO1B1 (0.54) | SLCO1B1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL22230668 | 0.86 | SLCO1B1 (0.41) | SLCO1B1ABCB11LMNAMEN1KMT2A | |
| SCHEMBL22256653 | 0.80 | SLCO1B1 (0.38) | SLCO1B1ABCB11NPC1RAB9AS1PR1 | |
| SCHEMBL22257017 | 0.80 | SLCO1B1 (0.49) | SLCO1B1ABCB11LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912975-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |