Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256953 | 0.86 | SLCO1B1 (0.45) | SLCO1B1ABCB11TSHRSIGMAR1MEN1 | |
| SCHEMBL22256709 | 0.85 | SLCO1B1 (0.44) | SLCO1B1ABCB11TSHRSIGMAR1MEN1 | |
| SCHEMBL24043000 | 0.85 | SLCO1B1 (0.44) | SLCO1B1ABCB11TSHRSIGMAR1MEN1 | |
| SCHEMBL24287701 | 0.82 | SLCO1B1 (0.42) | SLCO1B1ABCB11TSHRSIGMAR1MEN1 | |
| SCHEMBL22256890 | 0.82 | SLCO1B1 (0.40) | SLCO1B1ABCB11SIGMAR1MEN1KMT2A | |
| SCHEMBL22257114 | 0.82 | SLCO1B1 (0.43) | SLCO1B1ABCB11TSHRSIGMAR1MEN1 | |
| SCHEMBL22230698 | 0.82 | SLCO1B1 (0.48) | SLCO1B1ABCB11SIGMAR1MEN1KMT2A | |
| SCHEMBL24042990 | 0.81 | SLCO1B1 (0.44) | SLCO1B1ABCB11PDE10A | |
| SCHEMBL22230663 | 0.80 | SLCO1B1 (0.39) | SLCO1B1ABCB11SIGMAR1MEN1KMT2A | |
| SCHEMBL22256989 | 0.79 | SLCO1B1 (0.49) | SLCO1B1ABCB11SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912975-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |