Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 20/20 | 0.98 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.98 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.98 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.98 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.98 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.98 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.98 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.98 |
| ▸ | LPAR3 | Q9UBY5 | 13/20 | 0.76 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14794837 | 1.00 | LPAR1 (0.98) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| Bms-986020 SCHEMBL344742 | 0.99 | LPAR1 (1.00) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| Bms-986020 SCHEMBL343068 | 0.99 | LPAR1 (1.00) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| Bms-986020 SCHEMBL14590 | 0.99 | LPAR1 (1.00) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL343858 | 0.96 | LPAR1 (0.94) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL343859 | 0.96 | LPAR1 (0.94) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL2761567 | 0.95 | LPAR1 (0.90) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL12973623 | 0.95 | LPAR1 (0.90) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL343865 | 0.95 | LPAR1 (0.93) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL343864 | 0.95 | LPAR1 (0.93) | LPAR1ABCC3ABCC4ABCB11CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912975-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |