Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258495 | 0.99 | KCNQ3 (0.40) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL22258825 | 0.89 | CLK2 (0.40) | MAPTSMN1; SMN2STAT3TRPV1KDM4E | |
| SCHEMBL22258494 | 0.86 | MAPT (0.41) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL22258827 | 0.85 | MAPT (0.40) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL22235966 | 0.84 | KCNQ3 (0.52) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL22258273 | 0.83 | KCNQ3 (0.51) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL22258230 | 0.83 | NPC1 (0.40) | KCNQ3KCNQ2MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL22258478 | 0.82 | NPC1 (0.41) | KCNQ3KCNQ2MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL22258493 | 0.82 | KCNQ3 (0.44) | KCNQ3KCNQ2TRPV1KDM4EPKM | |
| SCHEMBL22258452 | 0.79 | CLK2 (0.43) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |