SCHEMBL22259554

SCHEMBL22259554

O=C(C1CC1)N1CCC(Cn2c(-c3ccc(-c4ccc5occc5c4)cc3)nc3ccc(Br)cc32)C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FASN P49327 18/20 0.57
BRD4 O60885 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10304 1.00 FASN (0.57) FASNBRD4
SCHEMBL10303 1.00 FASN (0.57) FASNBRD4
SCHEMBL22220865 0.91 FASN (0.60) FASNBRD4
SCHEMBL11909361 0.91 FASN (0.60) FASNBRD4
SCHEMBL10111 0.91 FASN (0.60) FASNBRD4
SCHEMBL10472 0.90 FASN (0.57) FASN
SCHEMBL10473 0.90 FASN (0.57) FASN
SCHEMBL14274 0.89 FASN (0.59) FASNBRD4
SCHEMBL22220891 0.89 FASN (0.59) FASNBRD4
SCHEMBL11909194 0.89 FASN (0.59) FASNBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020150423-A1 METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS YUMANITY THERAPEUTICS, INC. (US) 2020-07-23 WO disclosed