Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 13/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656 | 1.00 | FASN (0.47) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL13657 | 1.00 | FASN (0.47) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL11909586 | 0.94 | FASN (0.48) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL11891 | 0.94 | FASN (0.48) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL10794 | 0.93 | FASN (0.52) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL10795 | 0.93 | FASN (0.52) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL11198 | 0.92 | BRD4 (0.51) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL22259585 | 0.92 | BRD4 (0.51) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL11197 | 0.92 | BRD4 (0.51) | FASNBRD4BRD2EP300BRD3 | |
| SCHEMBL22220804 | 0.90 | FASN (0.50) | FASNBRD4BRD2EP300BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |