Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.61 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905 | 1.00 | FASN (0.61) | FASNMELKACACBACACA | |
| SCHEMBL10906 | 1.00 | FASN (0.61) | FASNMELKACACBACACA | |
| SCHEMBL10853 | 0.88 | FASN (0.64) | FASNMELKACACBACACA | |
| SCHEMBL10852 | 0.88 | FASN (0.64) | FASNMELKACACBACACA | |
| SCHEMBL10597 | 0.88 | FASN (0.64) | FASNMELK | |
| SCHEMBL22259551 | 0.88 | FASN (0.64) | FASNMELK | |
| SCHEMBL10801 | 0.88 | FASN (0.64) | FASNMELKACACBACACA | |
| SCHEMBL10800 | 0.88 | FASN (0.64) | FASNMELKACACBACACA | |
| SCHEMBL10596 | 0.88 | FASN (0.64) | FASNMELK | |
| SCHEMBL22259650 | 0.87 | BRD4 (0.47) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |