Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432328 | 0.97 | KMT2A (0.68) | KMT2AMEN1KDM4ESMN1; SMN2HIF1A | |
| SCHEMBL1531771 | 0.91 | MEN1 (0.73) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29551049 | 0.90 | KMT2A (0.75) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1926570 | 0.90 | KMT2A (0.63) | KMT2AMEN1KDM4ESMN1; SMN2HIF1A | |
| SCHEMBL222127 | 0.89 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1531938 | 0.88 | KMT2A (0.78) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12768363 | 0.88 | KMT2A (0.78) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12768693 | 0.86 | MEN1 (0.66) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL223023 | 0.86 | MEN1 (0.71) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22089857 | 0.86 | MEN1 (0.87) | KMT2AMEN1SMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022605-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-8349210-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120003401-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003401-A1 | MESOGENIC STABILIZERS | PYM1, BMI1, C1S | KMT2A 375/4885MEN1 17/4885KDM4E 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.