⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494425 | 0.71 | — | — | |
| SCHEMBL5029938 | 0.70 | CES1 (0.44) | — | |
| SCHEMBL816002 | 0.68 | — | — | |
| SCHEMBL11927524 | 0.67 | — | — | |
| SCHEMBL31126656 | 0.67 | — | — | |
| SCHEMBL4856747 | 0.67 | CA1 (0.31) | — | |
| SCHEMBL6222225 | 0.65 | CA1 (0.33) | — | |
| SCHEMBL19725734 | 0.64 | KDM4E (0.33) | — | |
| SCHEMBL9510557 | 0.64 | HTR2A (0.35) | — | |
| Hydrochloric Acid SCHEMBL6220561 | 0.64 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136718-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2023-05-04 | — | — | US | disclosed |
| EP-3914230-A1 | <SMALLCAPS/>? ? ?FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, Llc (US) | 2021-12-01 | — | — | EP | disclosed |
| US-20200261605-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC | 2020-08-20 | — | — | US | disclosed |
| WO-2020154623-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2020-07-30 | — | — | WO | disclosed |