SCHEMBL2226829

SCHEMBL2226829

O=c1oc2cc(O)ccc2cc1-c1c[nH]cn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.58
MIF P14174 15/20 0.57
PTGS1 P23219 1/20 0.57
NPC1 O15118 2/20 0.56
MEN1 O00255 2/20 0.53
RAB9A P51151 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
GLA P06280 1/20 0.53
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PIK3CD O00329 1/20 0.52
PIK3CB P42338 1/20 0.52
RXFP1 Q9HBX9 1/20 0.50
SIRT3 Q9NTG7 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15068792 0.83 HPGD (0.47) ESR2MIFPTGS1NPC1MEN1
SCHEMBL15542438 0.80 ESR2 (0.57) ESR2MIFPTGS1NPC1MEN1
SCHEMBL12814116 0.78 ESR2 (0.42) ESR2MIFMEN1RAB9AKMT2A
SCHEMBL12814289 0.76 ADORA2A (0.41) ESR2MIFNPC1MEN1RAB9A
SCHEMBL2166723 0.74 ESR2 (1.00) ESR2MIFPTGS1NPC1MEN1
SCHEMBL9829272 0.74 MIF (0.74) ESR2MIFPTGS1NPC1MEN1
SCHEMBL28142014 0.73 PTGS1 (1.00) ESR2MIFPTGS1NPC1MEN1
SCHEMBL17030237 0.72 ESR2 (0.77) ESR2MIFPTGS1NPC1MEN1
SCHEMBL7027339 0.72 TYR (0.43) ESR2NPC1MEN1RAB9AKMT2A
SCHEMBL591688 0.72 MIF (1.00) ESR2MIFPTGS1NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313261-A1 Biological Indicator Comprising Genetically-Modified Test Microorganism SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-05 US disclosed
US-20230193347-A1 Biological Indicator with Test Microorganisms Enveloped by Wax Composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-06-22 US disclosed
CN-116194158-A Biological indicator comprising genetically modified test microorganism 3M创新有限公司 2023-05-30 CN disclosed
US-20230110772-A1 Immobilized pH Indicator for Biological Indicator Growth Indication SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-04-13 US disclosed
US-20230047207-A1 Self-Contained Biological Indicator with Salt Compound SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-02-16 US disclosed
CN-115461468-A Biological indicator with test microorganisms encapsulated by wax composition 3M创新有限公司 2022-12-09 CN disclosed
CN-115315522-A Fixed pH indicator for biological indicator growth indication 3M创新有限公司 2022-11-08 CN disclosed
CN-114981399-A Self-contained biological indicator with salt compound 3M创新有限公司 2022-08-30 CN disclosed
WO-2021214595-A1 BIOLOGICAL INDICATOR WITH TEST MICROORGANISMS ENVELOPED BY WAX COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-10-28 WO disclosed
US-20210311002-A1 SELF-CONTAINED BIOLOGICAL INDICATOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-10-07 US disclosed
WO-2020023833-A1 SELF-CONTAINED BIOLOGICAL INDICATOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-01-30 WO disclosed
EP-2516666-B1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES CO (US) 2016-04-20 EP disclosed
CN-102686739-B Methods of detecting microorganisms and kits therefore 3M INNOVATIVE PROPERTIES CO 2014-09-24 CN disclosed
US-8802429-B2 System for detecting microorganisms 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-12 US disclosed
US-20130316443-A1 SYSTEM FOR DETECTING MICROORGANISMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-28 US disclosed
US-8518664-B2 Methods of determining the amount of microorganisms present in a test sample 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-27 US disclosed
EP-2516666-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M Innovative Properties Company (US) 2012-10-31 EP disclosed
US-20120252049-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US disclosed
CN-102686739-A Methods of detecting microorganisms and kits therefore 3M INNOVATIVE PROPERTIES CO 2012-09-19 CN disclosed
WO-2011087711-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed