Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268457 | 0.97 | ABCG2 (0.40) | ABCG2PTGER4CHEK1MEN1KMT2A | |
| SCHEMBL22268550 | 0.94 | CHEK1 (0.40) | ABCG2CHEK1KMT2AFFAR1FLT3 | |
| SCHEMBL22268549 | 0.94 | ABCG2 (0.35) | ABCG2PTGER4CHEK1MEN1KMT2A | |
| SCHEMBL22268463 | 0.94 | ABCG2 (0.42) | ABCG2CHEK1MEN1KMT2AATM | |
| SCHEMBL22268472 | 0.93 | ABCG2 (0.35) | ABCG2PTGER4CHEK1MEN1KMT2A | |
| SCHEMBL22268462 | 0.92 | ABCG2 (0.37) | ABCG2PTGER4FFAR1USP14 | |
| SCHEMBL22268465 | 0.92 | ABCG2 (0.39) | ABCG2PTGER4MEN1KMT2AELANE | |
| SCHEMBL20114643 | 0.92 | PTGER4 (0.39) | PTGER4CHEK1MEN1KMT2AATM | |
| SCHEMBL22268551 | 0.91 | STS (0.35) | ABCG2PTGER4MEN1KMT2AATM | |
| SCHEMBL22268532 | 0.91 | CYP11B1 (0.35) | ABCG2PTGER4CHEK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392247-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-07-29 | — | — | EP | disclosed |