Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 0.81 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457981 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL20291860 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL18963150 | 0.81 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29432691 | 0.81 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29457980 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL18963163 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL20291856 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29432690 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29432715 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL18963277 | 0.79 | KCNK3 (1.00) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386979-B1 | 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF THE TASK-1 AND TASK-2 CHANNELS FOR TREATING SLEEP-RELATED BREATHING DISORDERS | Bayer Pharma AG (DE) | 2020-07-29 | — | — | EP | disclosed |