Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 7/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EPOR | P19235 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271557 | 0.94 | TLR2 (0.39) | KMT2ATLR2TLR1GLO1BCHE | |
| SCHEMBL20009584 | 0.92 | KMT2A (0.47) | KMT2ATLR2TLR1GLO1PTPN1 | |
| SCHEMBL17751723 | 0.92 | KMT2A (0.47) | KMT2ATLR2TLR1GLO1PTPN1 | |
| SCHEMBL22271686 | 0.88 | KMT2A (0.39) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL20013144 | 0.88 | TLR2 (0.42) | KMT2ATLR2TLR1GLO1BCHE | |
| SCHEMBL20009555 | 0.86 | TLR2 (0.40) | KMT2ATLR2TLR1GLO1BCHE | |
| SCHEMBL17751720 | 0.86 | TLR2 (0.40) | KMT2ATLR2TLR1GLO1BCHE | |
| SCHEMBL20013276 | 0.82 | KMT2A (0.42) | KMT2ATLR2TLR1BCHEACHE | |
| SCHEMBL20013097 | 0.82 | KMT2A (0.43) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL22995924 | 0.81 | KMT2A (0.54) | KMT2ATLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778622-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3218392-B1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2020-07-29 | — | — | EP | disclosed |