Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 10/20 | 0.76 |
| ▸ | KLK14 | Q9P0G3 | 10/20 | 0.76 |
| ▸ | KLK5 | Q9Y337 | 10/20 | 0.76 |
| ▸ | CTSG | P08311 | 8/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CTRC | Q99895 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353427 | 0.86 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL18352964 | 0.83 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL30111990 | 0.82 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL16946276 | 0.82 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL18352893 | 0.81 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL18353554 | 0.78 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL22272031 | 0.76 | MEN1 (1.00) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL912875 | 0.75 | KLK7 (0.85) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL4202365 | 0.75 | MEN1 (0.75) | KLK7KLK14KLK5CTSGMEN1 | |
| SCHEMBL913416 | 0.75 | KLK7 (1.00) | KLK7KLK14KLK5CTSGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097085-B1 | BENZOXAZINONE DERIVATIVES FOR TREATMENT OF SKIN DISEASES | SIXERA PHARMA AB (SE) | 2020-07-29 | — | — | EP | disclosed |