Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252334 | 1.00 | TYK2 (0.33) | TYK2MALT1PDE4DJAK1JAK2 | |
| SCHEMBL22252368 | 1.00 | TYK2 (0.33) | TYK2MALT1PDE4DJAK1JAK2 | |
| SCHEMBL22252471 | 1.00 | TYK2 (0.33) | TYK2MALT1PDE4DJAK1JAK2 | |
| SCHEMBL31161633 | 0.87 | TYK2 (0.40) | TYK2MALT1PDE4D | |
| SCHEMBL31161680 | 0.87 | TYK2 (0.40) | TYK2MALT1PDE4D | |
| SCHEMBL22272928 | 0.81 | TYK2 (0.39) | TYK2PDE4D | |
| SCHEMBL22272925 | 0.81 | TYK2 (0.39) | TYK2PDE4D | |
| SCHEMBL22252393 | 0.79 | MALT1 (0.36) | MALT1 | |
| SCHEMBL31161399 | 0.79 | TYK2 (0.48) | TYK2PDE4D | |
| SCHEMBL31161333 | 0.78 | SSTR3 (0.35) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154474-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-07-30 | — | — | WO | disclosed |