Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.40 |
| ▸ | CNR1 | P21554 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14222007 | 0.81 | CNR2 (0.54) | CNR2CNR1ALDH1A1 | |
| SCHEMBL2227038 | 0.77 | CNR2 (0.58) | CNR2CNR1ALDH1A1EPHX2 | |
| SCHEMBL14647182 | 0.74 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL15219064 | 0.73 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL13391917 | 0.73 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL15491977 | 0.73 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL12289472 | 0.72 | CNR2 (0.53) | CNR2 | |
| SCHEMBL15492715 | 0.72 | CNR2 (0.53) | CNR2 | |
| SCHEMBL17689399 | 0.71 | POLB (0.52) | CNR2ALDH1A1EPHX2 | |
| SCHEMBL14647393 | 0.70 | CNR2 (0.49) | CNR2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523936-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011088015-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-21 | — | — | WO | disclosed |