Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908240 | 1.00 | HPGD (0.41) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7908243 | 1.00 | HPGD (0.41) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7908244 | 1.00 | HPGD (0.41) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9405908 | 0.97 | HPGD (0.40) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9405910 | 0.97 | HPGD (0.40) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7908250 | 0.96 | HPGD (0.43) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7908246 | 0.96 | HPGD (0.43) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9405977 | 0.95 | HPGD (0.39) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9405978 | 0.95 | HPGD (0.39) | HPGDGAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9405887 | 0.95 | HPGD (0.39) | HPGDGAAMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |