SCHEMBL22277315

SCHEMBL22277315

CCCCCC1CCC(C2CCC(C3CCC(COc4ccc(OCC)c(F)c4F)CO3)CC2)CC1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.31
HTR1A P08908 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12759181 0.99 HTR2A (0.31) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12759182 0.96 HTR2A (0.32) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12759146 0.94 HTR2A (0.32) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12759206 0.94 SMN1; SMN2 (0.31)
SCHEMBL12759167 0.93 SGPL1 (0.33)
SCHEMBL12759194 0.93 HTR2C (0.31) HTR2AHTR2B
SCHEMBL12760284 0.92 HTR2A (0.32) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12760078 0.92 HTR2A (0.32) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12759145 0.91 HTR2C (0.33) ADRB2HTR1ASLC6A2HTR2ASLC6A4
SCHEMBL12759178 0.91 HTR2A (0.33) ADRB2HTR1ASLC6A2HTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed