Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.83 |
| ▸ | PPARD | Q03181 | 10/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279220 | 0.93 | PPARA (0.82) | PPARAPPARDKCNH2SCN10AALDH1A1 | |
| SCHEMBL22263424 | 0.91 | PPARA (1.00) | PPARAPPARDKCNH2SCN10AALDH1A1 | |
| SCHEMBL22263425 | 0.91 | PPARA (1.00) | PPARAPPARDKCNH2SCN10AALDH1A1 | |
| SCHEMBL22393988 | 0.90 | PPARA (0.70) | PPARAPPARDKCNH2KMT2AMEN1 | |
| SCHEMBL22394057 | 0.87 | PPARA (0.66) | PPARAPPARDKCNH2 | |
| SCHEMBL22393987 | 0.87 | PPARA (0.66) | PPARAPPARDKCNH2 | |
| SCHEMBL22279124 | 0.84 | PPARA (0.80) | PPARAPPARDKCNH2ALDH1A1MAPT | |
| SCHEMBL22263440 | 0.83 | PPARA (1.00) | PPARAPPARDKCNH2SCN10AALDH1A1 | |
| SCHEMBL22263441 | 0.83 | PPARA (1.00) | PPARAPPARDKCNH2SCN10AALDH1A1 | |
| SCHEMBL22279206 | 0.82 | PPARA (0.81) | PPARAPPARDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| US-20200239429-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885KCNH2 1993/4885 |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885KCNH2 1993/4885 |
| US-20200239429-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885KCNH2 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.