Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922822 | 0.90 | GCGR (0.86) | GCGR | |
| SCHEMBL19922907 | 0.85 | GCGR (0.65) | GCGR | |
| SCHEMBL19922780 | 0.82 | GCGR (1.00) | GCGR | |
| SCHEMBL19922820 | 0.82 | GCGR (0.81) | GCGR | |
| SCHEMBL19922776 | 0.80 | GCGR (0.79) | GCGR | |
| SCHEMBL19922811 | 0.80 | GCGR (0.78) | GCGR | |
| SCHEMBL19922855 | 0.80 | GCGR (0.69) | GCGR | |
| SCHEMBL19922783 | 0.79 | GCGR (0.77) | GCGR | |
| SCHEMBL19922764 | 0.79 | GCGR (0.77) | GCGR | |
| SCHEMBL19922844 | 0.79 | GCGR (0.76) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510022-B1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-05 | — | — | EP | disclosed |