Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517689 | 1.00 | CHRM1 (0.39) | CHRM1ALDH1A1KCNH2MITFPOLB | |
| SCHEMBL12518013 | 0.85 | CHRM1 (0.39) | CHRM1ALDH1A1KCNH2MITFCACNA1C | |
| SCHEMBL12519001 | 0.85 | CHRM1 (0.39) | CHRM1ALDH1A1KCNH2MITFCACNA1C | |
| SCHEMBL12517690 | 0.82 | CHRM1 (0.40) | CHRM1ALDH1A1KCNH2PKMKMT2A | |
| SCHEMBL12517688 | 0.82 | CHRM1 (0.40) | CHRM1ALDH1A1KCNH2PKMKMT2A | |
| SCHEMBL18031624 | 0.81 | CHRM1 (0.41) | CHRM1ALDH1A1KCNH2MITFPKM | |
| SCHEMBL2224358 | 0.80 | CHRM1 (0.38) | CHRM1ALDH1A1KCNH2MITF | |
| SCHEMBL2224363 | 0.80 | CHRM1 (0.38) | CHRM1ALDH1A1KCNH2MITF | |
| SCHEMBL2224186 | 0.80 | CHRM1 (0.39) | CHRM1ALDH1A1KCNH2PKMPTGS1 | |
| SCHEMBL2224191 | 0.80 | CHRM1 (0.39) | CHRM1ALDH1A1KCNH2PKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087995-A2 | ORGANIC COMPOUNDS | BARRY CLIFTON (US) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011087995-A2 | ORGANIC COMPOUNDS | BARRY CLIFTON (US) | 2011-07-21 | — | — | WO | disclosed |