Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | NQO1 | P15559 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22283275 | 1.00 | KCNA3 (0.70) | KCNA3ABCG2NR1H4MAOBBCHE | |
| SCHEMBL29906111 | 0.85 | ABCB1 (0.72) | KCNA3MAOBMAOAABCB1CYP3A4 | |
| SCHEMBL6845894 | 0.85 | ABCB1 (0.72) | KCNA3MAOBMAOAABCB1CYP3A4 | |
| SCHEMBL29929521 | 0.85 | ABCB1 (0.72) | KCNA3MAOBMAOAABCB1CYP3A4 | |
| SCHEMBL25194422 | 0.84 | ABCG2 (0.79) | KCNA3ABCG2NR1H4MAOBBCHE | |
| SCHEMBL30382949 | 0.84 | ABCG2 (0.79) | KCNA3ABCG2NR1H4MAOBBCHE | |
| SCHEMBL29225587 | 0.83 | SLC5A1 (0.68) | ABCG2MAOBBCHEMAOAABCB1 | |
| SCHEMBL5441725 | 0.83 | SLC5A1 (0.68) | ABCG2MAOBBCHEMAOAABCB1 | |
| SCHEMBL25194265 | 0.83 | MAOB (0.75) | ABCG2NR1H4MAOBBCHEMAOA | |
| SCHEMBL20472672 | 0.82 | ABCG2 (0.85) | ABCG2NR1H4MAOBBCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11559512-B2 | Composition for prevention, alleviation, and/or treatment of heat illness | TOYO UNIVERSITY (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20200297694-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT ILLNESS | TOYO UNIVERSITY (JP) | 2020-09-24 | — | — | US | disclosed |
| EP-3689345-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT STROKE | Toyo University (JP) | 2020-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559512-B2 | Composition for prevention, alleviation, and/or treatment of heat illness | TNF, HSF1, HSP90AA1 | KCNA3 2497/4885ABCG2 2617/4885NR1H4 327/4885 |
| US-20200297694-A1 | COMPOSITION FOR PREVENTION, ALLEVIATION, AND/OR TREATMENT OF HEAT ILLNESS | TNF, HSF1, HSP90AA1 | KCNA3 2497/4885ABCG2 2617/4885NR1H4 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.