Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288395 | 1.00 | PDE3B (0.60) | PDE3BPDE3AHRH3 | |
| SCHEMBL22288538 | 0.82 | PDE3B (0.59) | PDE3BPDE3A | |
| SCHEMBL30966660 | 0.82 | PDE3B (0.59) | PDE3BPDE3A | |
| SCHEMBL22288558 | 0.80 | PDE3B (0.42) | PDE3BPDE3AHRH3 | |
| SCHEMBL22318024 | 0.80 | PDE3B (0.42) | PDE3BPDE3AHRH3 | |
| SCHEMBL22288534 | 0.80 | PDE3B (0.42) | PDE3BPDE3AHRH3 | |
| SCHEMBL22317381 | 0.80 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL20703083 | 0.78 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL22318100 | 0.76 | PDE3B (0.65) | PDE3BPDE3AHRH3 | |
| SCHEMBL22288550 | 0.76 | PDE3B (0.57) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157199-A1 | ANNULATED DIHYDROPYRIDAZINONE COMPOUNDS AS ANTI-CANCER COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | claimed |
| WO-2020157199-A1 | ANNULATED DIHYDROPYRIDAZINONE COMPOUNDS AS ANTI-CANCER COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |