Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304780 | 0.90 | MAOB (0.45) | MAOBPDE3BPDE3AGPR119 | |
| SCHEMBL22304871 | 0.86 | PDE3B (0.47) | MAOBPDE3BPDE3A | |
| SCHEMBL22288613 | 0.81 | PDE3B (0.50) | MAOBPDE3BPDE3A | |
| SCHEMBL22288965 | 0.77 | MAOB (0.56) | MAOBPDE3BPDE3A | |
| SCHEMBL22304519 | 0.77 | SCN9A (0.43) | MAOBPDE3BPDE3A | |
| SCHEMBL22288910 | 0.77 | SCN9A (0.43) | MAOBPDE3BPDE3A | |
| SCHEMBL22304685 | 0.76 | PDE3B (0.58) | MAOBPDE3BPDE3A | |
| SCHEMBL22304766 | 0.76 | PDE3B (0.51) | MAOBPDE3BPDE3A | |
| SCHEMBL22304763 | 0.75 | MAOB (0.56) | MAOBPDE3BPDE3A | |
| SCHEMBL22288624 | 0.74 | MAOB (0.56) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | claimed |
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020157201-A1 | OXADIAZINONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |