Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 3/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.38 |
| ▸ | CCL2 | P13500 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223664 | 0.90 | BRD4 (0.47) | LMNABRD4SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL224530 | 0.90 | BRD4 (0.47) | LMNABRD4SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL224531 | 0.90 | BRD4 (0.47) | LMNABRD4SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL225382 | 0.90 | BRD4 (0.45) | LMNACYP3A4BRD4SMN1; SMN2TSHR | |
| SCHEMBL224220 | 0.87 | KMT2A (0.43) | LMNACYP1A2CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL15890804 | 0.87 | BRD4 (0.45) | LMNACYP3A4BRD4SMN1; SMN2TSHR | |
| SCHEMBL223584 | 0.85 | SIRT2 (0.45) | LMNASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL222991 | 0.80 | SMN1; SMN2 (0.56) | LMNABRD4SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL225279 | 0.80 | BRD4 (0.46) | BRD4SMN1; SMN2KMT2ABRD2BRD3 | |
| SCHEMBL224343 | 0.80 | BRD4 (0.46) | BRD4SMN1; SMN2KMT2ABRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004197-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | KOWA COMPANY, LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004197-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | EPOR, HBG1, HBG2 | LMNA 4334/4885CYP1A2 2178/4885CYP3A4 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.