Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 13/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974768 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL10310201 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL13998899 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL5531089 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL20696269 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL31018747 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL8294081 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2NPSR1KDM1ACNR1MAOA | |
| SCHEMBL11486071 | 0.81 | SSTR4 (0.49) | SMN1; SMN2NPSR1KDM1AMAOAMAOB | |
| SCHEMBL11486073 | 0.81 | SSTR4 (0.49) | SMN1; SMN2NPSR1KDM1AMAOAMAOB | |
| SCHEMBL11492971 | 0.80 | SSTR4 (0.51) | SMN1; SMN2NPSR1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |