Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021414 | 0.89 | KDM4E (0.42) | KDM4EATML3MBTL1RORCAKR1C4 | |
| SCHEMBL21913084 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1RORCTSHR | |
| SCHEMBL21416133 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1RORCTSHR | |
| SCHEMBL24900283 | 0.85 | KDM4E (0.44) | KDM4EATML3MBTL1RORCTSHR | |
| SCHEMBL13672108 | 0.85 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL25833076 | 0.82 | KDM4E (0.40) | KDM4EATML3MBTL1HDAC4RORC | |
| SCHEMBL21418276 | 0.82 | KDM4E (0.41) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL24609412 | 0.82 | KDM4E (0.41) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL24059858 | 0.81 | KDM4E (0.35) | KDM4EATML3MBTL1RORCTSHR | |
| SCHEMBL24521419 | 0.81 | KDM4E (0.40) | KDM4EATML3MBTL1HDAC4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689882-A1 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | Universal Display Corporation (US) | 2020-08-05 | — | — | EP | disclosed |