Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 19/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18692211 | 0.89 | CFTR (0.75) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692106 | 0.89 | CFTR (0.79) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693146 | 0.88 | CFTR (0.70) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692718 | 0.87 | CFTR (0.68) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693677 | 0.87 | CFTR (0.69) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692816 | 0.86 | CFTR (0.77) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693828 | 0.86 | CFTR (0.68) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693237 | 0.86 | CFTR (0.64) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692302 | 0.86 | CFTR (0.64) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693462 | 0.86 | CFTR (0.64) | CFTRCYP2C9HRH1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3359541-B1 | N-SULFONYLATED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE | ABBVIE OVERSEAS SARL (LU) | 2020-08-05 | — | — | EP | disclosed |