Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.77 |
| ▸ | EGFR | P00533 | 15/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21707230 | 0.87 | BTK (1.00) | BTKEGFR | |
| SCHEMBL22222665 | 0.87 | BTK (0.70) | BTKEGFR | |
| SCHEMBL21706984 | 0.85 | BTK (1.00) | BTKEGFR | |
| SCHEMBL21706983 | 0.79 | BTK (1.00) | BTKEGFR | |
| SCHEMBL22457564 | 0.74 | BTK (0.69) | BTKEGFR | |
| SCHEMBL29044572 | 0.74 | BTK (0.55) | BTKEGFR | |
| SCHEMBL21706936 | 0.72 | BTK (1.00) | BTKEGFR | |
| SCHEMBL21707234 | 0.72 | BTK (1.00) | BTKEGFR | |
| SCHEMBL23865995 | 0.72 | BTK (0.54) | BTKEGFR | |
| SCHEMBL21706944 | 0.71 | BTK (1.00) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689871-A1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |