Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922100 | 0.92 | GCGR (0.74) | GCGR | |
| SCHEMBL19922079 | 0.92 | GCGR (0.88) | GCGR | |
| SCHEMBL19922240 | 0.87 | GCGR (0.82) | GCGR | |
| SCHEMBL19922111 | 0.85 | GCGR (0.85) | GCGR | |
| SCHEMBL19922194 | 0.85 | GCGR (1.00) | GCGR | |
| SCHEMBL19922176 | 0.84 | GCGR (0.82) | GCGR | |
| SCHEMBL19922108 | 0.83 | GCGR (0.82) | GCGR | |
| SCHEMBL20273108 | 0.83 | GCGR (0.61) | GCGR | |
| SCHEMBL19922241 | 0.83 | GCGR (0.79) | GCGR | |
| SCHEMBL19922192 | 0.82 | GCGR (1.00) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510026-B1 | INDAZOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-12 | — | — | EP | disclosed |
| EP-3510028-B1 | INDAZOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-05 | — | — | EP | disclosed |