Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296319 | 0.87 | SLC6A2 (0.50) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL28276509 | 0.82 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1572105 | 0.81 | SLC6A2 (0.64) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL17832229 | 0.80 | SLC6A2 (0.52) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL20782030 | 0.80 | TAAR1 (0.40) | SLC6A2TAAR1CYP2D6LMNA | |
| SCHEMBL20819751 | 0.79 | SLC6A2 (0.57) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL28754247 | 0.79 | TAAR1 (0.44) | TAAR1ALDH1A1 | |
| SCHEMBL19329101 | 0.79 | SLC6A2 (0.57) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL21862853 | 0.78 | SLC6A2 (0.45) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL22296342 | 0.77 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426032-B1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-05 | — | — | EP | disclosed |