Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18346920 | 0.86 | HRH2 (0.56) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11214613 | 0.81 | HRH2 (0.57) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10782626 | 0.81 | HRH2 (0.51) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11279095 | 0.80 | HRH2 (0.50) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL10784425 | 0.80 | HRH2 (0.50) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL7278989 | 0.80 | HRH2 (0.63) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL5879530 | 0.79 | CYP1A2 (0.50) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL8481913 | 0.78 | HRH2 (0.62) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL10782629 | 0.78 | HRH2 (0.52) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Hydrochloric Acid SCHEMBL17726945 | 0.78 | HRH2 (0.62) | HRH2SLC22A2CA12SLC22A3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3018125-B1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | SHIN NIPPON BIOMEDICAL LABORATORIES LTD (JP) | 2020-08-05 | — | — | EP | disclosed |