Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.41 |
| ▸ | KYNU | Q16719 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 16/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894234 | 0.91 | ITGAL (0.43) | ITGALKYNUITGB2ICAM1 | |
| SCHEMBL13894119 | 0.90 | ITGAL (0.41) | ITGALKYNUITGB2ICAM1 | |
| SCHEMBL18867782 | 0.85 | ITGAL (0.43) | ITGALITGB2ICAM1 | |
| SCHEMBL17992463 | 0.82 | ITGAL (0.43) | ITGALITGB2ICAM1 | |
| SCHEMBL18868608 | 0.80 | ITGAL (0.45) | ITGALITGB2ICAM1 | |
| SCHEMBL23153579 | 0.79 | ITGAL (0.42) | ITGALITGB2ICAM1 | |
| SCHEMBL17991428 | 0.79 | ITGAL (0.42) | ITGALITGB2ICAM1 | |
| SCHEMBL16852204 | 0.79 | ITGAL (0.41) | ITGALITGB2ICAM1 | |
| SCHEMBL13894114 | 0.71 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL13894065 | 0.70 | ITGAL (0.48) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |