Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 2/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | KYNU | Q16719 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153599 | 0.93 | ITGAL (0.64) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL10112626 | 0.91 | ITGAL (0.65) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL19158608 | 0.89 | ITGAL (0.62) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL18883515 | 0.89 | ITGAL (0.61) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL18885225 | 0.89 | ITGAL (0.61) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL19157785 | 0.88 | ITGAL (0.63) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL4926853 | 0.88 | ITGAL (0.63) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL13894422 | 0.88 | ITGAL (0.65) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL18883796 | 0.87 | ITGAL (0.61) | ITGALITGB1ITGA5ITGA4ITGAV | |
| SCHEMBL19157989 | 0.84 | ITGAL (0.54) | ITGALITGB1ITGA5SLC16A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |