SCHEMBL2229686

SCHEMBL2229686

CCCCCc1ccc(N)c(N)c1CCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.43
SKP2 Q13309 1/20 0.42
CYP3A4 P08684 2/20 0.41
MAPT P10636 2/20 0.41
ALOX5 P09917 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TLR8 Q9NR97 4/20 0.39
LIPG Q9Y5X9 2/20 0.38
HTR2A P28223 1/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2421197 0.98 TYR (0.46) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL28320527 0.98 TYR (0.46) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL3806265 0.94 SKP2 (0.47) TYRSKP2CYP3A4MAPTALOX5
Hydrochloric Acid SCHEMBL6536044 0.92 SKP2 (0.46) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL2400391 0.86 TYR (0.44) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL2400771 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL1187291 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL11483332 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL1704787 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTALOX5
SCHEMBL1705721 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139977-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2012-09-05 EP claimed
US-7977286-B2 Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-07-12 US claimed
EP-2195402-A2 CATALYTIC ANTIOXIDANTS ExxonMobil Research and Engineering Company (US) 2010-06-16 EP claimed
EP-2139977-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-06 EP claimed
EP-2029706-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2009-03-04 EP claimed
WO-2009025774-A2 CATALYTIC ANTIOXIDANTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-02-26 WO claimed
WO-2008123940-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-16 WO claimed
WO-2007133462-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-11-22 WO claimed
EP-1186595-B1 Diaryl-p-phenylenediamine disulfides GOODYEAR TIRE & RUBBER (US) 2003-11-26 EP claimed
CN-118291198-A Method for reducing abnormal combustion events 英菲诺姆国际有限公司 2024-07-05 CN disclosed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
CN-117903862-A Lubricating oil composition 英菲诺姆国际有限公司 2024-04-19 CN disclosed
CN-117866128-A Functionalization C 4 to 5 Olefin polymer and lubricant composition containing the same 英菲诺姆国际有限公司 2024-04-12 CN disclosed
CN-117866686-A Lubricant composition containing metal alkanoate 英菲诺姆国际有限公司 2024-04-12 CN disclosed
US-5750786-A CONDENSATION OF ANILINE OR ALKYLPHENYLAMINE WITH A DIHYDROXYBENZENE CATALYZED BY MIXTURE OF TITANIUM CHLORIDE OR ALUMINUM CHLORIDE AND IRON OXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-12 US disclosed
US-5750786-A CONDENSATION OF ANILINE OR ALKYLPHENYLAMINE WITH A DIHYDROXYBENZENE CATALYZED BY MIXTURE OF TITANIUM CHLORIDE OR ALUMINUM CHLORIDE AND IRON OXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-12 US disclosed
US-4967609-A Flexible boot KEEPER CO., LTD. (JP) 1990-11-06 US disclosed
US-4269763-A STABILIZERS FOR DIENE RUBBERS PREPARED BY REACTING HYDROQUINONE WITH A MIXTURE OF O-TOLUIDINE, XYLIDENE MIXTURE AND ANILINE; MELTING POINTS; OXIDATION AND OZONE RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-05-26 US disclosed
US-4256669-A SOLVENT EXTRACTION AND ALKYLATION WITH AROMATIC AMINE TO PRODUCE DIARYL PARA-PHENYLENEDIAMINES MALLINCKRODT, INC. (US) 1981-03-17 US disclosed
US-4224247-A Recovery of para-aminophenol MALLINCKRODT, INC. (US) 1980-09-23 US disclosed