Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.64 |
| ▸ | ITGAL | P20701 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12188988 | 1.00 | ITGB2 (0.64) | ITGB2ICAM1ITGAL | |
| SCHEMBL12188965 | 0.95 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867802 | 0.94 | ITGB2 (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL17992451 | 0.93 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867803 | 0.93 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868632 | 0.93 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756075 | 0.93 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL12169785 | 0.93 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912265 | 0.92 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL12169930 | 0.91 | ITGB2 (0.63) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |