Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.57 |
| ▸ | ITGAL | P20701 | 20/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755918 | 0.89 | ITGB2 (0.72) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13821853 | 0.83 | ITGB2 (0.63) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13821872 | 0.83 | ITGB2 (0.66) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL20618491 | 0.81 | ITGB2 (0.82) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13821849 | 0.81 | ITGB2 (0.82) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868122 | 0.78 | ITGB2 (0.56) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13822006 | 0.78 | ITGB2 (0.56) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL10129729 | 0.77 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL10129730 | 0.77 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868534 | 0.75 | ITGB2 (0.70) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |