Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.66 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.66 |
| ▸ | ITGAL | P20701 | 19/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12169793 | 1.00 | ITGB2 (0.66) | ITGB2ICAM1ITGALCYP2C9ALDH1A1 | |
| SCHEMBL12054460 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP2C9ALDH1A1 | |
| SCHEMBL18868499 | 0.92 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP2C9ALDH1A1 | |
| SCHEMBL19157599 | 0.91 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP2C9ALDH1A1 | |
| SCHEMBL18867833 | 0.89 | ITGB2 (0.65) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL28765684 | 0.87 | ITGB2 (0.64) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL28730913 | 0.86 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL28730910 | 0.86 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL29402123 | 0.86 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL20683216 | 0.84 | ITGB2 (0.52) | ITGB2ICAM1ITGALCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | NOVARTIS AG (CH) | 2020-08-05 | — | — | EP | disclosed |