Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 19/20 | 0.80 |
| ▸ | KDM5A | P29375 | 1/20 | 0.60 |
| ▸ | KDM5C | P41229 | 1/20 | 0.60 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20870101 | 0.99 | PDE9A (0.79) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870243 | 0.99 | PDE9A (0.79) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870403 | 0.89 | PDE9A (1.00) | PDE9A | |
| SCHEMBL20870397 | 0.89 | PDE9A (1.00) | PDE9A | |
| SCHEMBL20870241 | 0.89 | PDE9A (0.76) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL22871654 | 0.88 | PDE9A (0.77) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870608 | 0.87 | PDE9A (0.80) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870263 | 0.87 | PDE9A (0.83) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870611 | 0.87 | PDE9A (0.76) | PDE9AKDM5AKDM5CKDM5B | |
| SCHEMBL20870254 | 0.86 | PDE9A (0.81) | PDE9AKDM5AKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939588-A1 | USES OF PHOSPHODIESTERASE INHIBITORS | Transthera Sciences (Nanjing), Inc. (CN) | 2022-01-19 | — | — | EP | disclosed |
| EP-3689876-A1 | PDE9 INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co. Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |