Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.50 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576877 | 1.00 | MCHR1 (0.50) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL22298789 | 1.00 | MCHR1 (0.50) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL31576987 | 1.00 | MCHR1 (0.50) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL31576904 | 1.00 | MCHR1 (0.50) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL31576933 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL22299139 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL22299146 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL31577174 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL22298785 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL31577269 | 0.95 | KCNQ3 (0.51) | MCHR1KCNQ3KCNQ2KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |