SCHEMBL22299252

SCHEMBL22299252

NCCCCCCCCCC(=O)Nc1ccc(NCc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.56
HDAC1 Q13547 6/20 0.52
HDAC3 O15379 5/20 0.52
HDAC8 Q9BY41 5/20 0.52
HDAC2 Q92769 4/20 0.52
HDAC10 Q969S8 4/20 0.52
HDAC11 Q96DB2 4/20 0.52
HDAC6 Q9UBN7 4/20 0.52
MTOR P42345 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
KCNQ3 O43525 1/20 0.46
KCNQ2 O43526 1/20 0.46
KCNQ4 P56696 1/20 0.46
KCNQ5 Q9NR82 1/20 0.46
MCHR1 Q99705 1/20 0.46
NCOR2 Q9Y618 1/20 0.45
RORC P51449 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22299257 1.00 FFAR1 (0.56) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL22298800 1.00 FFAR1 (0.56) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL29769957 0.88 EPHX2 (0.54) HDAC1HDAC3HDAC8HDAC2HDAC10
SCHEMBL22298749 0.88 KCNQ3 (0.59) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL22298799 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL31577003 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL22299249 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL31577122 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL22299261 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2
SCHEMBL31577186 0.87 HDAC1 (0.49) FFAR1HDAC1HDAC3HDAC8HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP claimed
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP disclosed
WO-2020157126-A1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF Università degli Studi di Salerno (IT) 2020-08-06 WO disclosed