Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229364 | 0.98 | HTT (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2228321 | 0.98 | HTT (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2227904 | 0.98 | HTT (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2230391 | 0.98 | HTT (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2228630 | 0.98 | HTT (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2228193 | 0.97 | GGPS1 (0.49) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2227740 | 0.91 | GGPS1 (0.51) | LMNAHTTHSP90AA1RAD52APAF1 | |
| SCHEMBL2870315 | 0.87 | HTT (0.62) | LMNAHTTRAD52APAF1ALDH1A1 | |
| SCHEMBL5286313 | 0.85 | HTT (0.66) | LMNAHTTHSP90AA1RAD52SMN1; SMN2 | |
| SCHEMBL5293081 | 0.85 | HTT (0.66) | LMNAHTTHSP90AA1RAD52SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730157-B1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1730157-A1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GmbH (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005105815-A1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |