Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.66 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.66 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299363 | 0.86 | KCNQ3 (0.49) | KCNQ3KCNQ2HPGDNPC1RAB9A | |
| SCHEMBL22299365 | 0.84 | KCNQ3 (0.62) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22288452 | 0.84 | KCNQ3 (0.59) | KCNQ3KCNQ2KCNQ4KCNQ5ASPH | |
| SCHEMBL31577178 | 0.83 | KCNQ2 (0.68) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22288442 | 0.83 | KCNQ2 (0.68) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22298759 | 0.83 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22298758 | 0.83 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22298764 | 0.83 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22298762 | 0.83 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL22298760 | 0.83 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | claimed |
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |