Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299159 | 1.00 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KCNQ2KCNQ3 | |
| SCHEMBL22299349 | 0.87 | KCNQ2 (0.49) | MAPTSMN1; SMN2ALDH1A1KCNQ2KCNQ3 | |
| SCHEMBL22299350 | 0.87 | KCNQ2 (0.49) | MAPTSMN1; SMN2ALDH1A1KCNQ2KCNQ3 | |
| SCHEMBL22299155 | 0.86 | MCHR1 (0.43) | MAPTSMN1; SMN2ALDH1A1KCNQ2MCHR1 | |
| SCHEMBL31577154 | 0.86 | MCHR1 (0.43) | MAPTSMN1; SMN2ALDH1A1KCNQ2MCHR1 | |
| SCHEMBL31576964 | 0.86 | MCHR1 (0.43) | MAPTSMN1; SMN2ALDH1A1KCNQ2MCHR1 | |
| SCHEMBL31577143 | 0.86 | KCNQ2 (0.49) | MAPTSMN1; SMN2ALDH1A1KCNQ2KCNQ3 | |
| SCHEMBL31576974 | 0.86 | KCNQ2 (0.49) | MAPTSMN1; SMN2ALDH1A1KCNQ2KCNQ3 | |
| SCHEMBL22299449 | 0.85 | MCHR1 (0.44) | MAPTSMN1; SMN2ALDH1A1KCNQ2MCHR1 | |
| SCHEMBL31576882 | 0.85 | MCHR1 (0.44) | MAPTSMN1; SMN2ALDH1A1KCNQ2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | claimed |
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | disclosed |
| WO-2020157126-A1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | Università degli Studi di Salerno (IT) | 2020-08-06 | — | — | WO | disclosed |